Why Vaxxinity (VAXX) Shares Are Trading Higher Today - Vaxxinity (OTC:VAXX)

Vaxxinity Inc (NASDAQ:VAXX) announced data demonstrating durable lowering of low-density lipoprotein (LDL) cholesterol in non-human primates.
The company also selected VXX-401 to pursue as its anti-PCSK9 vaccine candidate to treat hypercholesterolemia.
The company plans to start Phase 1 clinical trial in early 2023.
VXX-401 is a synthetic peptide vaccine that targets proprotein convertase subtilisin/kexin type 9 serine protease (PCSK9) to lower low-density lipoprotein (LDL) cholesterol, a mechanism proven to reduce the risk of cardiovascular events.
The new data in non-human primates demonstrate that VXX-401 is well tolerated and provides long-lasting, significant LDL reduction versus placebo.
After a 6-week priming regimen with VXX-401, LDL cholesterol progressively dropped to 40-50% of placebo values in healthy monkeys.
A steady-state reduction of LDL cholesterol was observed for months. The magnitude of LDL reduction with VXX-401 was similar to that of a single dose of a monoclonal antibody comparator.
While LDL levels returned to baseline within 2-3 weeks after a single dose of a monoclonal antibody, a steady-state and long-lasting reduction of LDL levels was observed after the last dose of VXX-401.
Levels of "good" high-density lipoprotein (HDL) cholesterol were not affected by treatment and remained stable.
Price Action: VAXX shares are up 8.28% at $2.08 during the market session on the last check Tuesday.

Vaxxinity's Vaccine Candidate Shows Durable Cholesterol Lowering Activity In Animal Models