Adverum Biotechnologies Cuts Workforce, Prioritizes ADVM-022

  • Adverum Biotechnologies Inc ADVM announced a restructuring plan, including reductions in headcount and expenses, to prioritize its clinical development of ADVM-022, a single intravitreal injection for wet age-related macular degeneration (AMD).
  • Adverum intends these restructuring measures to fully support its ADVM-022 development plan, providing it with additional resources beyond one-year topline results from its Phase 2 LUNA trial.
  • The company is reducing its workforce by 78 (approximately 38%). 
  • Adverum expects the workforce reduction to decrease its annual operating costs by approximately $15.3 million in direct labor costs.
  • The company estimates to incur restructuring charges of approximately $4.2 million, to be recorded primarily in Q3 2022. 
  • The company is preparing to initiate the Phase 2 LUNA trial of ADVM-022.
  • The LUNA trial will evaluate two doses in 72 patients with wet AMD.
  • Truist Securities upgrades Adverum to Buy, with a price target raised to $4.
  • Price Action: ADVM shares are up 4.70% at $1.28 during the premarket session on the last check Thursday.
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