Oncorus, Gaeta Therapeutics Ink Cancer Candidate Licensing Agreement

Oncorus Inc ONCR has signed an exclusive licensing agreement with Gaeta Therapeutics Ltd, related to the use of locally delivered Interleukin-12 (IL-12) via oncolytic viral expression in combination with an immune checkpoint inhibitor.
IL-12 is one of five immunomodulatory payloads in Oncorus' lead viral immunotherapy product candidate, ONCR-177.
Oncorus is enrolling patients in a Phase 1 trial to evaluate ONCR-177 alone and combined with Merck & Co Inc's MRK Keytruda (pembrolizumab) in patients with advanced or refractory cutaneous, subcutaneous or metastatic nodal or with liver metastases of solid tumors.
Gaeta will receive an upfront payment of $0.2 million and is eligible to receive up to $7.5 million in milestone payments on a product-by-product and indication-by-indication basis.
Being developed for multiple solid tumor indications, ONCR-177 is an intratumorally administered oncolytic Herpes Simplex Virus (HSV)-based viral immunotherapy engineered to induce immunogenic cancer cell death.
Price Action: ONCR shares traded lower by 0.18% at $10.80 on the last check Thursday.

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