Scynexis Presents Interim Ibrexafungerp Data In Hospital-Based Fungal Infections

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  • Scynexis Inc SCYX announced an oral presentation of interim data analyses from its ongoing Phase 3 FURI study of oral ibrexafungerp in severe hospital-based fungal infections.
  • Related Link: Scynexis' Brexafemme For Vaginal Yeast Infections Secures 10 Years Regulatory Exclusivity.
  • Of the 74 patients treated with oral ibrexafungerp 62.1% showed complete or partial response, 24.3% achieved stable disease, 6.8% showed progressive disease, and 5.4% were indeterminate. 
  • One patient died due to an unrelated cause.
  • In addition, Scynexis is presenting two posters that discuss sub-populations from the FURI study with difficult-to-treat infections.
  • The presentation highlights a sub-analysis of 24 patients (83.3% were refractory) from the Phase 3 FURI study with esophageal candidiasis (EC) or oropharyngeal candidiasis (OPC) treated with oral ibrexafungerp. 
  • Of these patients, 62.5% showed complete or partial response, 29.2% achieved stable disease, and 16.7% showed progressive disease.
  • Sub-analysis of eight patients with Candida bone and joint infections from the Phase 3 FURI study showed 62.5% showed complete or partial response, 12.5% achieved stable disease, and 12.5% showed progressive disease. 
  • One patient was considered indeterminate.
  • Price Action: SCYX is down 1.24% at $5.41 during the market session on the last check Wednesday.
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