Theratechnologies' IV Push Form Of HIV Treatment At Par With IV Infusion

  • Theratechnologies Inc THTX has announced results from a study evaluating an intravenous (IV) push form of Trogarzo (ibalizumab-uiyk) for HIV-1 infection.
  • The TMB-302 study was conducted by the Company's partner, TaiMed Biologics, to evaluate the current Trogarzo IV Infusion with a more convenient IV Push form that can be infused within 30 seconds without dilution to the 15-minute infusion time of the original IV Infusion.  
  • Data showed consistent and statistically significant results demonstrating no difference in pharmacokinetics between IV Push and IV Infusion. 
  • The proportion of subjects with mean trough serum drug concentration equal or exceeding the target concentration was also the same for both administration forms. 
  • Additionally, no serious adverse events were observed, and drug-related adverse events were considered mild to moderate.
  • The Company plans to file a supplemental application with the FDA in Q4 of 2021.
  • Secondary endpoints were also achieved, confirming no difference in HIV-1 viral load due to the change from IV Infusion to IV Push. Additionally, there were no anti-Trogarzo antibodies or immunogenicity concerns.
  • Theratechnologies and TaiMed are currently evaluating an intramuscular (IM) method of administration for Trogarzo.
  • Patient screening is planned for Q4 of 2021.
  • Price Action: THTX shares are up 2.80% at $3.67 during the market session on the last check Wednesday.

Posted In: BriefsHIVBiotechNewsPenny StocksHealth CareSmall CapMoversTrading IdeasGeneral

Ad Disclosure: The rate information is obtained by Bankrate from the listed institutions. Bankrate cannot guaranty the accuracy or availability of any rates shown above. Institutions may have different rates on their own websites than those posted on Bankrate.com. The listings that appear on this page are from companies from which this website receives compensation, which may impact how, where, and in what order products appear. This table does not include all companies or all available products.

All rates are subject to change without notice and may vary depending on location. These quotes are from banks, thrifts, and credit unions, some of whom have paid for a link to their own Web site where you can find additional information. Those with a paid link are our Advertisers. Those without a paid link are listings we obtain to improve the consumer shopping experience and are not Advertisers. To receive the Bankrate.com rate from an Advertiser, please identify yourself as a Bankrate customer. Bank and thrift deposits are insured by the Federal Deposit Insurance Corp. Credit union deposits are insured by the National Credit Union Administration.

Consumer Satisfaction: Bankrate attempts to verify the accuracy and availability of its Advertisers' terms through its quality assurance process and requires Advertisers to agree to our Terms and Conditions and to adhere to our Quality Control Program. If you believe that you have received an inaccurate quote or are otherwise not satisfied with the services provided to you by the institution you choose, please click here.

Rate collection and criteria: Click here for more information on rate collection and criteria.