Oric Pharma To Launch Human Trial For CD73 Inhibitor Program In Q4

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  • The FDA has signed off Oric Pharmaceuticals Inc's ORIC Investigational New Drug Application (IND) for ORIC-533.
  • The Company can now proceed into a first-in-human clinical trial in which ORIC-533 will be tested as a single agent in an undisclosed tumor type not currently known to be under clinical evaluation with any other CD73 inhibitor. 
  • Oric will enroll its first patient in this trial during Q4 of 2021. 
  • During Q4 of 2021, the Company plans to host an R&D event to disclose the tumor indication along with the supporting preclinical rationale and data.
  • ORIC-533 is a highly potent, orally bioavailable small molecule inhibitor of CD73, a key node in the adenosine pathway believed to play a central role in resistance to chemotherapy and immunotherapy-based treatment regimens.
  • Read Next: Oric Pharma's ORIC-101 Shows Tumor Regression, Prolonged Stable Disease in Multiple Heavily Pretreated Tumors.
  • Related content: Benzinga's Full FDA Calendar.
  • Price Action: ORIC stock is up 4.85% at $25.73 during the premarket session on the last check Tuesday.
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Posted In: BiotechNewsHealth CareSmall CapFDAMoversTrading IdeasGeneralBriefsoncologyPhase 1 Trial
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