Lilly's Lebrikizumab Shows Clinical Benefit In Late-Stage Atopic Eczema Trials - Eli Lilly and Co (NYSE:LLY)

Eli Lilly And Co's LLY lebrikizumab ADvocate 1 and ADvocate 2 Phase 3 clinical trials met primary and all key secondary endpoints at Week 16.
Lebrikizumab significantly improved skin clearance and itch in people with moderate-to-severe atopic dermatitis (AD) in the two Phase 3 trials.
Results demonstrated that more than half of the patients achieved at least 75% clearance to total clearance on lebrikizumab monotherapy.
Lebrikizumab is a novel monoclonal antibody (mAb) that binds soluble IL-13 with high affinity, has high bioavailability, has a long half-life, and blocks IL-13 signaling.
The FDA has granted Fast Track designation to lebrikizumab.
The full study results from ADvocate 1 and ADvocate 2 will be disclosed at future congresses in 2022.
The most common adverse events included conjunctivitis, nasopharyngitis, and headache for lebrikizumab-treated patients.
Discontinuations due to adverse events were similar in the lebrikizumab group (1.4%) compared to placebo (1.7%).
Price Action: LLY shares closed at $264.21 on Friday.