OncoSec Stock Jumps On Anti-Cancer Gene Therapy Trial Collaboration With Merck In Melanoma

  • OncoSec Medical Inc ONCS will evaluate its DNA-plasmid interleukin-12 (IL-12) TAVO (tavokinogene telseplasmid) with Merck & Co Inc's MRK Keytruda (pembrolizumab) in KEYNOTE-C87 Phase 3 trial. 
  • The planned trial will evaluate the overall survival of patients treated with the TAVO / Keytruda combination versus standard of care in late-stage patients with metastatic melanoma who are refractory to immune checkpoint therapy. 
  • Under the terms of the Agreement, each party will be responsible for its internal costs, with OncoSec covering third-party expenses.  
  • KEYNOTE-C87 intends to enroll approximately 400 patients. 
  • TAVO has received FDA Fast Track designation as an anti-cancer gene therapy that expresses IL-12 to treat metastatic melanoma, following progression on Keytruda or Bristol-Myers Squibb Co's BMY Opdivo (nivolumab).  
  • Price Action: ONCS shares are up 24.37% at $3.47 during the premarket session on the last check Wednesday.
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Posted In: BiotechNewsPenny StocksHealth CareGeneralBriefscancergene therapymelanomaPhase 3 Trial
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