Sanofi, Translate Bio Initiate Human Trial Of mRNA COVID-19 Vaccine Candidate

Sanofi SA (NASDAQ: SNY) and Translate Bio Inc (NASDAQ: TBIO) have started a human trial of their mRNA COVID-19 vaccine candidate, dubbed MRT5500.

  • The event has triggered a milestone payment of $25 million to Translate Bio.
  • The Phase 1/2 trial will evaluate the safety, reactogenicity (tolerability), and immunogenicity (immune response) of MRT5500.
  • Participants will receive either a single dose of the vaccine or two doses 21 days apart, while three dose levels (15µg, 45µg or 135µg) will be examined.
  • Interim results are expected in the third quarter of 2021.
  • Last month, Sanofi and GlaxoSmithKline Plc (NYSE: GSKlaunched a new Phase 2 trial of an adjuvanted recombinant protein-based COVID-19 vaccine candidate, an attempt to revive their vaccine development efforts after a setback in December last year
  • Price Action: SNY shares are up 0.7% at $48.17, TBIO shares are up 3.20% at $24.85 in premarket trading on the last check Friday.

Posted In: COVID-19 VaccinePhase 2 TrialBiotechNewsHealth CareSmall CapFDAGeneral

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