U.S. stocks traded mostly higher toward the end of trading, with the Nasdaq Composite gaining around 50 points on Wednesday.

The Dow traded down 0.01% to 33,736.15 while the NASDAQ rose 0.42% to 13,619.46. The S&P 500 also rose, gaining, 0.14% to 4,364.45.

Check This Out: Top 5 Consumer Stocks That May Implode This Quarter

Leading and Lagging Sectors

Real estate shares surged by 1% on Wednesday.

In trading on Wednesday, energy shares fell by 1.6%.

Top Headline

Producer prices in the U.S. increased 0.5% month-over-month in September, versus a 0.7% rise in the prior month, but above market expectations of 0.3%.

Equities Trading UP

Tempest Therapeutics, Inc. (NASDAQ:TPST) shares shot up 1,713% to $4.35 after the company released new data demonstrating superiority of TPST-1120 arm across multiple study endpoints in first-line hepatocellular carcinoma study.

Shares of Phio Pharmaceuticals Corp. (NASDAQ:PHIO) got a boost, shooting 60% to $2.1695 after the company announced the poster presentation of two key preclinical studies of its INTASYL compound PH-894 at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics.

voxeljet AG (NASDAQ:VJET) shares were also up, gaining 31% to $1.35 after the company announced it was selected for a $14.9 million contract alongside GE Research to develop advanced manufacturing technologies to enable the U.S. energy transition.

Equities Trading DOWN

Silk Road Medical, Inc (NASDAQ:SILK) shares dropped 50% to $6.97 after the company announced preliminary third-quarter revenue results below estimates and issued FY23 revenue guidance below estimates.

Shares of E2open Parent Holdings, Inc. (NYSE:ETWO) were down 47% to $2.3050 as the company posted downbeat results for its second quarter and named Andrew Appel as interim CEO, effective immediately.

Also Check This Out: CSX To Rally Around 27%? Here Are 10 Other Analyst Forecasts For Wednesday

Commodities

In commodity news, oil traded down 2.5% to $83.78 while gold traded up 0.5% at $1,884.60.

Silver traded up 0.7% to $22.11 on Wednesday while copper fell 0.9% to $3.6005.

Euro zone

European shares closed mostly higher today. The eurozone’s STOXX 600 gained 0.15% London’s FTSE 100 fell 0.11% while Spain’s IBEX 35 Index rose 0.09% The German DAX rose 0.24% French CAC 40 slipped 0.44%, while Italy’s FTSE MIB Index gained 0.36%.

Germany’s consumer price inflation rate fell to 4.5% year-over-year in September from 6.1% in the prior month.

Asia Pacific Markets

Asian markets closed higher on Wednesday, with Japan’s Nikkei 225 gaining 0.60%, China’s Shanghai Composite Index gaining 0.12% and Hong Kong’s Hang Seng Index gaining 1.29%. India’s S&P BSE Sensex, meanwhile, rose 0.6%.

Chinese vehicle sales climbed by 9.5% year-over-year in September, recording the second straight month of growth. Japan's machine tool orders fell 11.2% year-over-year to JPY 133,913 million in September following a 17.6% decline in the prior month, while Reuters Tankan sentiment index for manufacturers in Japan was unchanged at +4 for October.

Economics

Mortgage applications in the U.S. rose by 0.6% in the week ending Oct. 6..

Producer prices in the U.S. increased 0.5% month-over-month in September, versus a 0.7% rise in the prior month, but above market expectations of 0.3%.

Now Read This: Apple, Amazon And 2 Other Stocks Insiders Are Selling