Clene's Lead Amyotrophic Lateral Sclerosis Shows Improved Function, Slowed Disease Progression

  • Clene Inc CLNN announced new results showing preserved ALS patient functional score (ALSFRS-R) and delayed time to clinical worsening from the most recent 12-month data cut of the open-label extension (OLE) of the Phase 2 RESCUE ALS trial in people with early amyotrophic lateral sclerosis (ALS) treated with CNM-Au8.
  • CNM-Au8 preserved physical function when given over 48 weeks as measured by the ALSFRS-R, a clinical assessment measuring activities such as walking, speaking, breathing, feeding, and dressing independently.
  • Related: Clene Shares Move Higher On Encouraging Data From Multiple Sclerosis Candidate.
  • Significant preservation of function (ALSFRS-R) from randomization to 48 weeks was observed, with significant preservation of function during the long-term open-label extension (OLE) week 24 to 120 weeks from randomization.
  • Significantly reduced risk of ALS clinical worsening by 52% over 120 weeks.
  • CNM-Au8 treatment was well-tolerated without long-term safety concerns.
  • Price Action: CLNN shares are up 4.17% at $1.25 on the last check Monday.
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