Gain Therapeutics Posts Encouraging Preclinical Data From Parkinson's, Alzheimer's Programs

  • Gain Therapeutics Inc GANX has presented new preclinical data from its Parkinson's and Alzheimer's Disease programs. 
  • These results were highlighted at the International Conference on Alzheimer's (AD) and Parkinson's Diseases (PD). 
  • The data shows that improving the lysosomal function through enhanced glucocerebrosidase (GCase) levels and activity can improve key pathological features in α-synucleinopathies and AD.
  • Related: Gain Therapeutics Stock Surges On Positive Preclinical Readout For Neurodegenerative Disease Drugs.
  • Orally bioavailable and brain-penetrant lead structurally targeted allosteric regulators (STARs) reduce neurotoxicity derived from the accumulation of toxic oligomeric species of Aβ and α-synuclein.
  • In mouse models, treatment with the STAR small molecule resulted in a decrease in neurotoxicity, motor deficit, neuroinflammation, and increase of neuronal survival.
  • Price Action: GANX shares are up 3.94% at $3.43 during the market session on the last check Tuesday.

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