Aileron Unveils Initial Data For Its Chemo Protective Agent

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  • Aileron Therapeutics Inc ALRN has announced initial findings from its ongoing study of ALRN-6924 in healthy volunteers. 
  • Data were presented at the International Society for Experimental Hematology (ISEH) 50th Annual Scientific Meeting. 
  • The initial findings demonstrated that a 0.3 mg/kg dose of ALRN-6924 was well tolerated.
  • It resulted in p53-mediated induction of the cell cycle inhibitor p21 in healthy, normal bone marrow cells without concurrent induction of apoptosis.
  • Related Content: Aileron Launches Early-Stage Study For Chemoprotective Candidate In Lung Cancer Settings.
  • Aileron will present final data from the Phase 1b small-cell lung cancer trial and additional data from the healthy volunteer study at the European Society for Medical Oncology (ESMO) Congress.
  • Price Action: ALRN shares are down 3.52% at $1.09 during the market session on the last check Friday.
Posted In: BiotechNewsPenny StocksHealth CareGeneralBriefschemotherapyPhase 1 Trial
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