Anixa Biosciences' COVID-19 Compounds Show Potential Efficacy Against Delta Variant

  • Anixa Biosciences Inc ANIX has announced that a genomic variant analysis indicates that its potential compounds may be more effective against the Delta variant than the original wild-type SARS-CoV-2. 
  • Anixa's program, in collaboration with European partner MolGenie, focuses on identifying novel, small molecule inhibitors of Mpro, the main protease of the virus. 
  • The current compounds that Anixa is synthesizing and evaluating have demonstrated their ability to inhibit the function of this protein, which the virus needs to replicate. 
  • Sequence analysis of several Delta variant samples demonstrates that the Mpro enzyme often has a mutation that replaces an asparagine (an amino acid) with leucine (another amino acid) near the binding site. 
  • This change makes the binding pocket of Mpro more hydrophobic, thus suggesting Anixa's compounds will be more potent inhibitors of the variant Mpro than the wild-type (original).
  • Price Action: ANIX shares are up 9.45% at $4.98 during the market session on the last check Wednesday.
  • Photo by Arek Socha from Pixabay

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