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Chris Howerton's Stock Ratings
Jefferies Analyst
Chris Howerton is an analyst at Jefferies. Analyst ratings are quantitative and qualitative analysis of a stock by Wall Street stock rating analysts. Stock ratings consist of expected future growth, current stock valuation and macroeconomic trends. Updated 12/15/2025
Updated: Dec 15, 2025
Overall Average Return
19.3%
Smart Score
Overall Average Return Percentile
75th
Number of Ratings
124
| Buy Now | Get Alert | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 12/11/2025 | GPCR | Buy Now | Structure Therapeutics | $67.83 | 84.3% | $79 → $125 | Maintains | Buy | Get Alert | |
| 01/02/2025 | ARDX | Buy Now | Ardelyx | $6.30 | 26.98% | $11 → $8 | Maintains | Buy | Get Alert | |
| 09/29/2023 | GPCR | Buy Now | Structure Therapeutics | $67.83 | 16.48% | $50 → $79 | Maintains | Buy | Get Alert | |
| 07/20/2023 | PNT | Buy Now | POINT Biopharma Global | — | — | $12 → $14 | Assumes | Buy → Buy | Get Alert | |
| 06/20/2023 | MIST | Buy Now | Milestone Pharmaceuticals | $2.48 | 61.62% | $8 → $4 | Downgrade | Buy → Hold | Get Alert | |
| 06/07/2023 | VERU | Buy Now | Veru | $2.42 | -58.68% | → $1 | Upgrade | Underperform → Hold | Get Alert | |
| 03/14/2023 | PRVB | Buy Now | Provention Bio | — | — | → $25 | Downgrade | Buy → Hold | Get Alert | |
| 03/10/2023 | BTAI | Buy Now | BioXcel Therapeutics | $1.92 | 1047.99% | $20 → $22 | Downgrade | Buy → Hold | Get Alert | |
| 02/28/2023 | GPCR | Buy Now | Structure Therapeutics | $67.83 | -49.87% | → $34 | Initiates | → Buy | Get Alert | |
| 02/08/2023 | AMTI | Buy Now | Applied Molecular | — | — | $0.8 → $0.4 | Downgrade | Hold → Underperform | Get Alert | |
| 02/08/2023 | AVTX | Buy Now | Avalo Therapeutics | $18.23 | -83.54% | → $3 | Downgrade | Hold → Underperform | Get Alert | |
| 02/08/2023 | CGEN | Buy Now | Compugen | $1.50 | -66.78% | → $0.5 | Downgrade | Hold → Underperform | Get Alert | |
| 02/08/2023 | URGN | Buy Now | UroGen Pharma | $22.19 | -54.93% | $35 → $10 | Downgrade | Buy → Hold | Get Alert | |
| 02/08/2023 | MEIP | Buy Now | MEI Pharma | — | — | $0.4 → $0.1 | Downgrade | Hold → Underperform | Get Alert | |
| 01/06/2023 | LABP | Buy Now | Landos Biopharma | — | — | $0.2 → $0.1 | Downgrade | Hold → Underperform | Get Alert | |
| 12/13/2022 | VECT | Buy Now | VectivBio Holding | — | — | → $18 | Initiates | → Buy | Get Alert | |
| 11/30/2022 | AVDL | Buy Now | Avadel Pharmaceuticals | $21.45 | -48.71% | $6.5 → $11 | Upgrade | Hold → Buy | Get Alert | |
| 11/18/2022 | PRVB | Buy Now | Provention Bio | — | — | $18 → $22 | Maintains | Buy | Get Alert | |
| 11/10/2022 | ISEE | Buy Now | IVERIC bio | — | — | $30 → $20 | Downgrade | Buy → Hold | Get Alert | |
| 11/10/2022 | APLS | Buy Now | Apellis Pharmaceuticals | $25.20 | 58.7% | $70 → $40 | Downgrade | Buy → Hold | Get Alert | |
| 10/14/2022 | HRMY | Buy Now | Harmony Biosciences | $39.26 | 55.37% | $57 → $61 | Upgrade | Hold → Buy | Get Alert | |
| 10/07/2022 | PRVB | Buy Now | Provention Bio | — | — | $10 → $15 | Maintains | Buy | Get Alert | |
| 09/30/2022 | AXSM | Buy Now | Axsome Therapeutics | $145.94 | -38.33% | $92 → $90 | Maintains | Buy | Get Alert | |
| 09/20/2022 | PRVB | Buy Now | Provention Bio | — | — | → $10 | Initiates | → Buy | Get Alert | |
| 08/10/2022 | AVDL | Buy Now | Avadel Pharmaceuticals | $21.45 | -62.7% | $6 → $8 | Downgrade | Buy → Hold | Get Alert | |
| 08/05/2022 | CGEN | Buy Now | Compugen | $1.50 | 32.89% | → $2 | Downgrade | Buy → Hold | Get Alert | |
| 08/03/2022 | HRMY | Buy Now | Harmony Biosciences | $39.26 | 45.19% | → $57 | Downgrade | Buy → Hold | Get Alert | |
| 07/07/2022 | AMTI | Buy Now | Applied Molecular | — | — | — | Downgrade | Buy → Hold | Get Alert | |
| 05/26/2022 | PNT | Buy Now | POINT Biopharma Global | — | — | → $20 | Upgrade | Hold → Buy | Get Alert | |
| 05/13/2022 | VERU | Buy Now | Veru | $2.42 | 2172.73% | $33 → $55 | Maintains | Buy | Get Alert | |
| 04/12/2022 | LABP | Buy Now | Landos Biopharma | — | — | $30 → $1.4 | Downgrade | Buy → Hold | Get Alert | |
| 04/04/2022 | FNCH | Buy Now | Finch Therapeutics Gr | $13.55 | 25.46% | $29 → $17 | Maintains | Buy | Get Alert | |
| 03/29/2022 | AXSM | Buy Now | Axsome Therapeutics | $145.94 | -47.24% | $71 → $77 | Maintains | Buy | Get Alert | |
| 03/25/2022 | MEIP | Buy Now | MEI Pharma | — | — | $4 → $1 | Downgrade | Buy → Hold | Get Alert | |
| 03/22/2022 | ISEE | Buy Now | IVERIC bio | — | — | → $27 | Initiates | → Buy | Get Alert | |
| 03/08/2022 | KRTX | Buy Now | Karuna Therapeutics | — | — | $180 → $183 | Maintains | Buy | Get Alert | |
| 03/03/2022 | AVTX | Buy Now | Avalo Therapeutics | $18.23 | -95.89% | $5 → $0.75 | Downgrade | Buy → Hold | Get Alert | |
| 03/02/2022 | ARDX | Buy Now | Ardelyx | $6.30 | -20.63% | $1 → $5 | Upgrade | Hold → Buy | Get Alert | |
| 03/01/2022 | GMTX | Buy Now | Gemini Therapeutics | — | — | $23 → $1.5 | Downgrade | Buy → Hold | Get Alert | |
| 02/25/2022 | VNDA | Buy Now | Vanda Pharma | $6.83 | 75.7% | $24 → $12 | Downgrade | Buy → Hold | Get Alert | |
| 02/03/2022 | MEIP | Buy Now | MEI Pharma | — | — | → $4 | Initiates | → Buy | Get Alert | |
| 12/14/2021 | ARNA | Buy Now | Arena Pharmaceuticals | — | — | → $100 | Downgrade | Buy → Hold | Get Alert | |
| 12/13/2021 | IGMS | Buy Now | IGM Biosciences | — | — | $101 → $126 | Maintains | Buy | Get Alert | |
| 11/30/2021 | IOBT | Buy Now | IO Biotech | $0.75 | 2550.76% | → $20 | Initiates | → Buy | Get Alert | |
| 09/17/2021 | CLDX | Buy Now | Celldex Therapeutics | $27.24 | 142.29% | → $66 | Initiates | → Buy | Get Alert | |
| 08/24/2021 | OMGA | Buy Now | Omega Therapeutics | — | — | → $30 | Initiates | → Buy | Get Alert | |
| 08/23/2021 | CADL | Buy Now | Candel Therapeutics | $6.10 | 260.66% | → $22 | Initiates | → Buy | Get Alert | |
| 08/19/2021 | APLS | Buy Now | Apellis Pharmaceuticals | $25.20 | 193.59% | → $74 | Initiates | → Buy | Get Alert | |
| 08/10/2021 | TCRX | Buy Now | TScan Therapeutics | $1.00 | 2001.89% | → $21 | Initiates | → Buy | Get Alert | |
| 07/28/2021 | KRTX | Buy Now | Karuna Therapeutics | — | — | → $158 | Initiates | → Buy | Get Alert | |
| 07/27/2021 | PNT | Buy Now | POINT Biopharma Global | — | — | → $8 | Initiates | → Hold | Get Alert | |
| 07/21/2021 | ARDX | Buy Now | Ardelyx | $6.30 | -68.25% | $11 → $2 | Downgrade | Buy → Hold | Get Alert | |
| 05/25/2021 | HOWL | Buy Now | Werewolf Therapeutics | $1.10 | 1900% | → $22 | Initiates | → Buy | Get Alert | |
| 04/20/2021 | CERC | Buy Now | Cerecor | — | — | → $4 | Initiates | → Buy | Get Alert | |
| 04/19/2021 | LVTX | Buy Now | LAVA Therapeutics | — | — | → $23 | Initiates | → Buy | Get Alert | |
| 04/13/2021 | VERU | Buy Now | Veru | $2.42 | 685.12% | → $19 | Initiates | → Buy | Get Alert | |
| 04/13/2021 | FNCH | Buy Now | Finch Therapeutics Gr | $13.55 | 114.02% | → $29 | Initiates | → Buy | Get Alert | |
| 04/12/2021 | EVLO | Buy Now | Evelo Biosciences | $0.00 | 17999900% | $11 → $18 | Upgrade | Hold → Buy | Get Alert | |
| 04/06/2021 | ACAD | Buy Now | ACADIA Pharmaceuticals | $26.96 | -22.11% | $40 → $21 | Downgrade | Buy → Hold | Get Alert | |
| 03/12/2021 | ZIOP | Buy Now | ZIOPHARM Oncology | — | — | $7 → $5 | Downgrade | Buy → Hold | Get Alert | |
| 03/03/2021 | GMTX | Buy Now | Gemini Therapeutics | — | — | → $23 | Initiates | → Buy | Get Alert | |
| 03/01/2021 | LABP | Buy Now | Landos Biopharma | — | — | → $32 | Initiates | → Buy | Get Alert | |
| 01/08/2021 | AXSM | Buy Now | Axsome Therapeutics | $145.94 | -11.61% | → $129 | Initiates | → Buy | Get Alert | |
| 12/10/2020 | PSTI | Buy Now | Pluristem Therapeutics | — | — | → $6 | Downgrade | Buy → Hold | Get Alert | |
| 09/15/2020 | IMMU | Buy Now | Immunomedics | — | — | $55 → $88 | Downgrade | Buy → Hold | Get Alert | |
| 09/14/2020 | HRMY | Buy Now | Harmony Biosciences | $39.26 | 29.9% | → $51 | Initiates | → Buy | Get Alert | |
| 09/02/2020 | BTAI | Buy Now | BioXcel Therapeutics | $1.92 | 4178.86% | → $82 | Initiates | → Buy | Get Alert | |
| 08/13/2020 | CHMA | Buy Now | Chiasma | — | — | → $8 | Initiates | → Buy | Get Alert | |
| 08/11/2020 | BLPH | Buy Now | Bellerophon Therapeutics | — | — | → $19 | Initiates | → Buy | Get Alert | |
| 08/11/2020 | MCRB | Buy Now | Seres Therapeutics | $16.20 | 79.01% | $4 → $29 | Upgrade | Hold → Buy | Get Alert | |
| 08/07/2020 | TXMD | Buy Now | TherapeuticsMD | $1.74 | -30.84% | $1.25 → $1.2 | Downgrade | Hold → Underperform | Get Alert | |
| 08/05/2020 | CORT | Buy Now | Corcept Therapeutics | $88.24 | -81.87% | → $16 | Downgrade | Buy → Hold | Get Alert | |
| 07/27/2020 | IMMU | Buy Now | Immunomedics | — | — | $41 → $55 | Maintains | Buy | Get Alert | |
| 07/24/2020 | PSTI | Buy Now | Pluristem Therapeutics | — | — | $12 → $16 | Maintains | Buy | Get Alert | |
| 07/24/2020 | MIST | Buy Now | Milestone Pharmaceuticals | $2.48 | 506.06% | $3 → $15 | Upgrade | Hold → Buy | Get Alert | |
| 07/15/2020 | PTGX | Buy Now | Protagonist Therapeutics | $95.00 | -71.58% | → $27 | Initiates | → Buy | Get Alert | |
| 06/30/2020 | AMTI | Buy Now | Applied Molecular | — | — | → $38 | Initiates | → Buy | Get Alert | |
| 06/19/2020 | PSTI | Buy Now | Pluristem Therapeutics | — | — | → $12 | Initiates | → Buy | Get Alert | |
| 06/19/2020 | ZIOP | Buy Now | ZIOPHARM Oncology | — | — | → $7 | Initiates | → Buy | Get Alert | |
| 05/26/2020 | LYRA | Buy Now | Lyra Therapeutics | $3.93 | 510.69% | → $24 | Initiates | → Buy | Get Alert | |
| 05/22/2020 | ARNA | Buy Now | Arena Pharmaceuticals | — | — | $62 → $69 | Maintains | Buy | Get Alert | |
| 05/18/2020 | ARNA | Buy Now | Arena Pharmaceuticals | — | — | → $62 | Initiates | → Buy | Get Alert | |
| 05/12/2020 | EVLO | Buy Now | Evelo Biosciences | $0.00 | 5999900% | $18 → $6 | Downgrade | Buy → Hold | Get Alert | |
| 04/16/2020 | ACAD | Buy Now | ACADIA Pharmaceuticals | $26.96 | 122.55% | → $60 | Initiates | → Buy | Get Alert | |
| 04/03/2020 | AVDL | Buy Now | Avadel Pharmaceuticals | $21.45 | -34.72% | → $14 | Initiates | → Buy | Get Alert | |
| 03/25/2020 | MIST | Buy Now | Milestone Pharmaceuticals | $2.48 | — | — | Downgrade | Buy → Hold | Get Alert | |
| 02/18/2020 | ARDX | Buy Now | Ardelyx | $6.30 | 74.6% | → $11 | Assumes | → Buy | Get Alert | |
| 09/24/2019 | CORT | Buy Now | Corcept Therapeutics | $88.24 | -77.33% | → $20 | Initiates | → Buy | Get Alert | |
| 06/03/2019 | MIST | Buy Now | Milestone Pharmaceuticals | $2.48 | 1031.31% | → $28 | Initiates | → Buy | Get Alert | |
| 04/30/2019 | EVLO | Buy Now | Evelo Biosciences | $0.00 | 17999900% | → $18 | Initiates | → Buy | Get Alert | |
| 04/30/2019 | MCRB | Buy Now | Seres Therapeutics | $16.20 | -56.79% | → $7 | Initiates | → Hold | Get Alert | |
| 11/08/2018 | VNDA | Buy Now | Vanda Pharma | $6.83 | 280.67% | → $26 | Initiates | → Buy | Get Alert | |
| 08/24/2018 | ARDX | Buy Now | Ardelyx | $6.30 | 11.11% | → $7 | Initiates | → Buy | Get Alert | |
| 10/06/2016 | VNDA | Buy Now | Vanda Pharma | $6.83 | — | — | Assumes | → Buy | Get Alert | |
| 08/09/2016 | CLDX | Buy Now | Celldex Therapeutics | $27.24 | -81.64% | $4 → $5 | Maintains | Hold | Get Alert | |
| 03/08/2016 | CLDX | Buy Now | Celldex Therapeutics | $27.24 | -85.32% | $31 → $4 | Downgrade | Buy → Hold | Get Alert | |
| 03/18/2015 | CLDX | Buy Now | Celldex Therapeutics | $27.24 | 32.16% | $24 → $36 | Maintains | Buy | Get Alert | |
| 03/12/2015 | ACAD | Buy Now | ACADIA Pharmaceuticals | $26.96 | 74.33% | $50 → $47 | Maintains | Buy | Get Alert | |
| 03/09/2015 | VNDA | Buy Now | Vanda Pharma | $6.83 | 192.83% | → $20 | Initiates | → Buy | Get Alert | |
| 02/20/2015 | VNDA | Buy Now | Vanda Pharma | $6.83 | 339.24% | $33 → $30 | Maintains | Market Outperform | Get Alert | |
| 01/28/2015 | ACAD | Buy Now | ACADIA Pharmaceuticals | $26.96 | 85.46% | $42 → $50 | Maintains | Buy | Get Alert | |
| 09/15/2014 | PSTI | Buy Now | Pluristem Therapeutics | — | — | $3.5 → $3 | Maintains | Hold | Get Alert | |
| 08/01/2013 | VNDA | Buy Now | Vanda Pharma | $6.83 | 104.98% | $13 → $14 | Maintains | Buy | Get Alert | |
| 07/30/2013 | VNDA | Buy Now | Vanda Pharma | $6.83 | 90.34% | $11 → $13 | Maintains | Buy | Get Alert | |
| 06/20/2013 | VNDA | Buy Now | Vanda Pharma | $6.83 | 61.05% | $7 → $11 | Maintains | Buy | Get Alert | |
| 06/19/2013 | CLDX | Buy Now | Celldex Therapeutics | $27.24 | -30.25% | $15 → $19 | Maintains | Buy | Get Alert | |
| 06/05/2013 | PSTI | Buy Now | Pluristem Therapeutics | — | — | $3.5 → $3 | Maintains | Hold | Get Alert | |
| 04/12/2013 | ACAD | Buy Now | ACADIA Pharmaceuticals | $26.96 | -33.23% | $13 → $18 | Maintains | Buy | Get Alert | |
| 04/05/2013 | ZIOP | Buy Now | ZIOPHARM Oncology | — | — | — | Terminates Coverage On | — | Get Alert | |
| 03/26/2013 | ZIOP | Buy Now | ZIOPHARM Oncology | — | — | $4 → $2 | Maintains | Hold | Get Alert | |
| 03/19/2013 | PSTI | Buy Now | Pluristem Therapeutics | — | — | → $3.5 | Initiates | → Hold | Get Alert | |
| 03/19/2013 | ACAD | Buy Now | ACADIA Pharmaceuticals | $26.96 | -51.78% | → $13 | Initiates | → Buy | Get Alert | |
| 03/08/2013 | CLDX | Buy Now | Celldex Therapeutics | $27.24 | -44.93% | $9 → $15 | Maintains | Buy | Get Alert | |
| 02/14/2013 | VNDA | Buy Now | Vanda Pharma | $6.83 | -12.15% | $3.5 → $6 | Upgrade | Hold → Buy | Get Alert | |
| 12/12/2012 | ZIOP | Buy Now | ZIOPHARM Oncology | — | — | $7 → $4 | Downgrade | Buy → Hold | Get Alert | |
| 12/10/2012 | CLDX | Buy Now | Celldex Therapeutics | $27.24 | -66.96% | $7 → $9 | Maintains | Buy | Get Alert | |
| 11/08/2012 | VNDA | Buy Now | Vanda Pharma | $6.83 | -48.76% | $4.5 → $3.5 | Maintains | Hold | Get Alert | |
| 11/07/2012 | ARNA | Buy Now | Arena Pharmaceuticals | — | — | $20 → $14 | Maintains | Buy | Get Alert | |
| 11/02/2012 | CLDX | Buy Now | Celldex Therapeutics | $27.24 | -74.3% | $6 → $7 | Maintains | Buy | Get Alert | |
| 11/01/2012 | CLDX | Buy Now | Celldex Therapeutics | $27.24 | -74.3% | $6 → $7 | Maintains | Buy | Get Alert | |
| 06/28/2012 | ARNA | Buy Now | Arena Pharmaceuticals | — | — | $9 → $20 | Maintains | Buy | Get Alert | |
| 05/11/2012 | ARNA | Buy Now | Arena Pharmaceuticals | — | — | $1 → $9 | Upgrade | Underperform → Buy | Get Alert | |
| 03/13/2012 | VNDA | Buy Now | Vanda Pharmaceuticals | $6.83 | -34.11% | $8.5 → $4.5 | Downgrade | Buy → Hold | Get Alert | |
| 03/02/2012 | ZIOP | Buy Now | Ziopharm Oncology | — | — | $7 → $6 | Maintains | Buy | Get Alert |
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