CBD For Traumatic Brain Injuries? Oral Administration Reduces Levels Of Neuronal Death In Animal Model, New Study

HempMeds, a subsidiary of Medical Marijuana, Inc. MJNA took part in a collaboration on a study to demonstrate the effectiveness of hemp-based CBD in the treatment of Parkinson's Disease. The company is also collaborating with the Center for Research and Advanced Studies of Neurological Diseases at the Siglo XXI National Medical Center, on a preclinical study in an animal model that demonstrated the ability to decrease extracellular glutamate levels that can lead to traumatic brain injuries.

This study, which was led by Dr. Luisa Rocha in conjunction with a large group of Mexican scientists, demonstrated the efficacy of oral administration of the company’s proprietary RSHO CBD product in the treatment of traumatic brain injuries, generated by a reduction in the excessive release of glutamate in the cerebral cortex.

“Through this controlled study, we were able to observe that the oral administration of cannabidiol during the seven days prior to an injury helped to avoid the over-release of glutamate that results from brain trauma, an effect associated with decreased mortality in neurons. In this study, it was also shown that the application of CBD helps sensorimotor improvement,” Dr. Rocha stated.

Glutamate is the main excitatory neurotransmitter of the central nervous system. Abnormally high levels of glutamate lead to a process called excitotoxicity, which can lead to death of neurons.

Dr. Rocha added: “The results obtained in this study help to understand how the oral application of cannabidiol reduces excitotoxicity caused by long-term traumatic brain injuries and facilitates functional recovery. In fact, pre-injury CBD treatment was sufficient to lessen the aftermath of traumatic brain injury.”

Blake Schroeder, CEO of Medical Marijuana, stated: “Clinically proving the therapeutic potential of CBD is at the core of our company’s ethos and the results of this study further proves the therapeutic value of plant based CBD. Through our research initiatives we continue to prove how CBD can positively affect patients worldwide. While federally funded research institutions in the US have been slow to embrace cannabis-based research, Latin American institutions have been performing this type of research in conjunction with our company for years. We will continue to pursue research in Mexico as well as in Brazil, where we are pursuing pharmaceutical registration of our products.”

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Photo by Esteban Lopez on Unsplash

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