Boston Scientific Posts Colorectal Cancer Survival Data For Tumor-Targeting Microbeads


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  • Boston Scientific Corporation (NYSE:BSX) announced that the EPOCH clinical trial of the TheraSphere Y-90 Glass Microspheres (TheraSphere treatment) met both primary endpoints.
  • The results of a long-term study showed that adding TheraSpheres to a standard chemotherapy regimen could extend survival for patients with colorectal cancer that has spread to the liver.
  • Each of the beads contains a small but mighty dose of Y-90, a radioactive isotope of yttrium with a half-life of fewer than three days. 
  • The beads are planted directly in a tumor by a catheter, helping minimize the dose and damage to nearby healthy tissues.
  • In the study, TheraSpheres were used in tandem with chemotherapy as a second-line treatment for liver-dominant colorectal cancer patients who saw their disease worsen either during or after their chemo. 
  • TheraSpheres were found to be 31% less likely than the control group to show disease progression or death due to any cause and just over 40% less likely to experience hepatic disease progression or death.
  • Earlier this year, TheraSpheres was approved by the FDA for hepatocellular carcinoma, the most common type of primary liver cancer. 
  • Related content: Benzinga's Full FDA Calendar.
  • Price Action: BSX stock closed lower by 1.63% at $43.65 on Monday.

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Posted In: NewsHealth CareFDAGeneralBriefscolorectal cancerLiver Cancer