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Calithera Biosciences, Inc. (NASDAQ:CALA) initiates dosing first patient in the phase 2 clinical trial evaluating its spleen tyrosine kinase (SYK) inhibitor mivavotinib (CB-659) in patients with relapsed/refractory non-germinal center B-cell like (non-GCB) diffuse large B-cell lymphoma (DLBCL).
The phase 2 clinical trial is an open-label multicenter study of mivavotinib monotherapy in patients with relapsed/refractory non-GCB DLBCL.
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Susan Molineaux, President and chief executive officer, said, “Mivavotinib has demonstrated potential to be a first-to-market approach for non-GCB DLBCL. This study will advance understanding of how our novel biomarker-driven approach could help address this high unmet therapeutic need.”
The company is planning to share data readout from this trial by first quarter of 2023.
Calithera believes that the data from the trial could position the company to initiate a study with registrational intent in biomarker-specific DLBCL populations.
Shares of Calithera are trading higher at $2.60 in the after hours session.
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New research shows the biggest crypto buyers are back. And this time? They could hold for the possibility that Bitcoin will surpass $100,000 in 2024. You don’t want to miss the next massive crypto bull run like we saw in 2020 and 2021. To know exactly what’s going on and what to buy… Get Access To Benzinga’s Best Crypto Research and Investments For Only $1.