Bulls vs Bears
Click to unlock major analysts' bullish and bearish positions by joining Benzinga Edge.

Market sentiment signals for Karyopharm Therapeutics (KPTI): analyst consensus, short interest, options flow and insider activity.
Analyst Consensus
Outperform
10 analysts
Options Flow (P/C)
0.17
More calls — Bullish
Avg Consensus PT
$32
+5251.2%
Highest Price Target
$75
+12441.8%
Lowest Price Target
$3
+401.7%
Short Interest
26.8%
Declining — Bullish
Insider Activity (30d)
Net Seller
Short Interest — % of Float
| Date | Firm | Analyst & Accuracy | Upside / Downside | PT Change | Action | Rating |
|---|---|---|---|---|---|---|
| Jul 31, 2026 | Piper Sandler | Edward Tenthoff— | +1070.6% | $16 → $7 | Maintained | Overweight |
| Jul 31, 2026 | HC Wainwright & Co. | Robert Burns— | +401.7% | $13 → $3 | Downgrade | Buy→Neutral |