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The 2022 OTCQX Best 50 – the top 50 performers on the OTCQX of the prior year – traded an aggregate of $594 million in average daily dollar volume in 2021, marking roughly a 383% increase from the respective $123 million in 2020.

According to OTC Markets Group Inc.’s (OTCQX:OTCM) latest announcement, the companies delivered a median total return of 81% to investors in 2021.

North American-based companies from Canada and the United States, such as Enzon Pharmaceuticals, Inc. (OTCQX:ENZN), Unrivaled Brands, Inc. (OTCQX:UNRV), and Corning Natural Gas Holding Corporation (OTCQX:CNIG), made up a majority of the list. Also represented were international companies from Euronext Amsterdam, the Hong Kong Stock Exchange, and the Australian Securities Exchange (ASX).

The constituents of the 2022 OTCQX Best 50 also exhibited relative diversity in their initiatives. Top-performer Nanalysis Scientific Corp. (OTCQX:NSCIF), for example, develops and manufactures nuclear magnetic resonance (NMR) devices. NSCIF shares the “top 50” designation with Wow Unlimited Media Inc. (OTCQX:WOWMF), an animation and entertainment company, Taal Distributed Technology Inc. (OTCQX:TAALF), an enterprise blockchain processing company, and Indiva Ltd. (OTCQX:NDVAF), a cannabis producer.

Adding to the diversity, a number of energy-driven securities make the 2022 OTCQX Best 50, as well as the three community banks: GrandSouth Bancorporation (OTCQX:GRRB), SVB&T Corp. (OTCQX:SVBT), and Coastal Carolina Bancshares Inc. (OTCQX:CCNB).

Recurring Appearances

Ten companies from last year’s ranking made their second appearance on the OTCQX Best 50 list in 2022. H2O Innovation Inc. (OTCQX:HEOFF) and Grayscale Bitcoin Trust’s (OTCQX: GBTC) inclusion in this year’s list marks their third consecutive appearance on the OTCQX Best 50.

IsoEnergy Ltd. (OTCQX:ISENF)
Global Atomic Corp. (OTCQX:GLATF)
Neo Lithium Corp. (OTCQX:NTTHF)
Deep Yellow Ltd. (OTCQX:DYLLF)
Grayscale Digital Large Cap Fund LLC (OTCQX:GDLC)
Converge Technology Solutions Corp. (OTCQX:CTSDF)
POET Technologies Inc. (OTCQX:POETF)
H2O Innovation Inc. (OTCQX:HEOFF)
NanoXplore Inc. (OTCQX:NNXPF)
Grayscale Bitcoin Trust (BTC) (OTCQX:GBTC)
Adventus Mining Corp. (OTCQX:ADVZF)

The 2022 OTCQX Best 50 Companies:

Rank	Company	Symbol
1	Nanalysis Scientific Corp.	(OTCQX:NSCIF)
2	Constantine Metal Resources Ltd.	(OTCQX:CNSNF)
3	InPlay Oil Corp.	(OTCQX:IPOOF)
4	Filo Mining Corp.	(OTCQX:FLMMF)
5	Journey Energy Inc.	(OTCQX:JRNGF)
6	Opsens, Inc.	(OTCQX:OPSSF)
7	Grayscale Ethereum Trust (ETH)	(OTCQX:ETHE)
8	IsoEnergy Ltd.	(OTCQX:ISENF)
9	Corsa Coal Corp.	(OTCQX:CRSXF)
10	Obsidian Energy Ltd.	(OTCQX:OBELF)
11	Global Atomic Corp.	(OTCQX:GLATF)
12	Neo Lithium Corp.	(OTCQX:NTTHF)
13	NOVONIX LTD.	(OTCQX:NVNXF)
14	Petrus Resources Ltd.	(OTCQX:PTRUF)
15	Grayscale Ethereum Classic Trust (ETC)	(OTCQX:ETCG)
16	Wow Unlimited Media Inc.	(OTCQX:WOWMF)
17	Labrador Gold Corp.	(OTCQX:NKOSF)
18	Western Uranium & Vanadium Corp.	(OTCQX:WSTRF)
19	Eloro Resources Ltd.	(OTCQX:ELRRF)
20	Taal Distributed Information Technologies Inc.	(OTCQX:TAALF)
21	Deep Yellow Ltd.	(OTCQX:DYLLF)
22	Torq Resources Inc.	(OTCQX:TRBMF)
23	Bombardier Inc.	(OTCQX:BDRBF) (OTCQX:BDRAF)
24	Coastal Carolina Bancshares Inc.	(OTCQX:CCNB)
25	Fission Uranium Corp.	(OTCQX:FCUUF)
26	Grayscale Digital Large Cap Fund LLC	(OTCQX:GDLC)
27	Indiva Ltd.	(OTCQX:NDVAF)
28	Millennial Lithium Corp.	(OTCQX:MLNLF)
29	Converge Technology Solutions Corp.	(OTCQX:CTSDF)
30	POET Technologies Inc.	(OTCQX:POETF)
31	4Front Ventures Corp.	(OTCQX:FFNTF)
32	Amerigo Resources Ltd.	(OTCQX:ARREF)
33	Enzon Pharmaceuticals Inc.	(OTCQX:ENZN)
34	Yankuang Energy Group Co. Ltd.	(OTCQX:YZCAY) (OTCQX:YZCHF)
35	ASM International N.V.	(OTCQX:ASMIY)
36	NioCorp Developments Ltd.	(OTCQX:NIOBF)
37	Thunderbird Entertainment Group Inc.	(OTCQX:THBRF)
38	SVB&T Corp.	(OTCQX:SVBT)
39	Nuvo Pharmaceuticals Inc.	(OTCQX:MRVFF)
40	Unrivaled Brands Inc.	(OTCQX:UNRV)
41	GOODNESS GROWTH HLDGS INC.	(OTCQX:GDNSF)
42	Ivanhoe Mines Ltd.	(OTCQX:IVPAF)
43	H2O Innovation Inc.	(OTCQX:HEOFF)
44	NanoXplore Inc.	(OTCQX:NNXPF)
45	Grayscale Bitcoin Trust (BTC)	(OTCQX:GBTC)
46	Corning Natural Gas Holding Corp.	(OTCQX:CNIG) (OTCQX:CNIGO) (OTCQX:CNIGP)
47	Table Trac Inc.	(OTCQX:TBTC)
48	MariMed Inc.	(OTCQX:MRMD)
49	Adventus Mining Corp.	(OTCQX:ADVZF)
50	GrandSouth Bancorporation	(OTCQX:GRRB)

More On The OTCQX Best 50

The OTCQX Best 50 is an annual ranking of the top 50 U.S. and international companies traded on the OTCQX Best Market, based on an equal weighting of one-year total return and average daily dollar volume growth. Companies in the 2022 OTCQX Best 50 were ranked based on their performance during the 2021 calendar year.

OTC Markets Group applied the following criteria to eligible companies traded on OTCQX on Dec. 31, 2021, to determine which companies would qualify for the 2022 OTCQX Best 50:

traded on OTCQX on Dec. 31, 2020
closing share price of $0.25 or greater on Dec. 31, 2021
closing share price on Dec. 31, 2021, greater than on Dec. 31, 2020
traded equal to or greater than $500,000 in dollar volume in 2021
not a “penny stock” on Dec. 31, 2021, as defined under U.S. Securities and Exchange Commission (SEC) Rule 3a51-1 of the Securities Exchange Act of 1934
member of the OTCQX Composite Index as of Dec. 31, 2021

View the complete 2022 OTCQX Best 50 ranking.

This post contains sponsored advertising content. This content is for informational purposes only and is not intended to be investing advice.

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