NeuroDerm's Latest Clinical Data Accepted as Late Breaking News to the International Parkinson and Movement Disorder Society's 19th International Congress

NeuroDerm NDRM, a clinical-stage pharmaceutical company developing drugs for central nervous system (CNS) diseases, announced the company will present its latest data of its lead products, ND0612L and ND0612H, at the International Parkinson and Movement Disorder Society's 19th International Congress of Parkinson's Disease and Movement Disorders meeting taking place on June 14 to 18, 2015 in San Diego, CA. ND0612L and ND0612H are NeuroDerm's proprietary, first ever liquid levodopa/carbidopa (LD/CD) formulations, intended to maintain steady levodopa plasma levels through simple, continuous subcutaneous delivery. They are designed to significantly improve the treatment of moderate and severe Parkinson's patients and to replace the need for highly invasive current therapies requiring surgical intervention such as Deep Brain Stimulation (DBS) and Duopa/Duodopa. Nir Giladi, MD, a Professor of the Sackler Faculty of Medicine at Tel Aviv University will present, "Pharmacokinetic Profile of ND0612L (LD/CD for subcutaneous infusion) in Patients with Moderate to Severe Parkinson's Disease," on Monday, June 15 from 12:30 to 2:00 PM PDT (Abstract number 226). Dr. Giladi is a recognized leader in the field of movement disorders. He is a chairman of the Department of Neurology at the Tel Aviv Sourasky Medical Center. He has served as an officer of the International Parkinson and Movement Disorders Society (MDS) since 2010. The abstract will be presented in a Guided Poster Tour Presentation during the MDS International Congress by Sheila Oren, MD, Vice President of Clinical and Regulatory Affairs at NeuroDerm Ltd., on June 18, 2015 at 12:00 - 1:30 PM PDT. The tour topic is titled "Parkinson's Disease: Neuropharmacology". The abstract will be available online on June 14. The company will also present data of the high-dose version of its ND0612 product candidate, ND0612H, intended for severe Parkinson's disease patients. The late-breaking poster LBA 08, "Stable Levodopa Plasma Levels with ND0612 (LD/CD for subcutaneous infusion) in Parkinson's disease (PD) patients with motor fluctuations," will be presented by Dr. Nir Giladi as well on Wednesday, June 17 from 12:00 to 1:30 PM PDT. As a late–breaking poster it will be displayed for the entire duration of the Scientific Program (Monday, June 15 – Thursday, June 18). In earlier studies, the company announced topline results for its Phase IIa pharmacokinetic study of ND6012H and ND0612L in December 2014. That study showed that continuous, subcutaneous delivery of its LC/DC product candidates led to clinically significant steady plasma levodopa levels, and that ND0612H reached plasma levodopa levels that should be sufficient to effectively treat the majority of patients considered as candidates for either DBS or DuoDopa.
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