PacBio Sequencing For Allele-Specific HLA Typing To Be Showcased At American Society For Histocompatibility And Immunogenetics Annual Meeting

Pacific Biosciences of California, Inc., PACB provider of the PacBio® RS II DNA Sequencing System, today announced that its unique Single Molecule, Real-Time (SMRT®) Sequencing technology will be featured in a number of presentations at the 2014 American Society for Histocompatibility and Immunogenetics (ASHI) 40th Annual Meeting taking place October 20-24 in Denver, CO. "With industry-leading read lengths, accuracy, and fast turnaround time, the PacBio RS II can sequence full-length HLA gene alleles and reliably provide directly phased HLA types without imputation," said Kevin Corcoran, Senior Vice President of Market Development for Pacific Biosciences. "We have received a lot of interest over the past year in HLA applications on our platform and are excited to participate in the ASHI conference to showcase our unique solution and discuss emerging immunogenomic research applications." Attendees at the meeting can learn more about SMRT Sequencing at the following presentations: Podium Presentations: Tuesday, October 21 Session: New & Improved NGS 2:00 p.m. - 3:30 p.m. OR01: Automated Assembly of Complex Immunogenetic Haplotypes Using Long-Read, Single Molecule, Real-Time Sequencing of Fosmids Richard J. Hall, Ph.D., Pacific Biosciences, Menlo Park, CA OR05: Complete Resequencing of Extended Genomic Regions Using Fosmid Target Capture and Single Molecule Real-Time (SMRT®) Long Read Sequencing Technology Daniel Geraghty, Ph.D., Fred Hutchinson Cancer Research Center, Seattle, WA Thursday, October 23 Session: Scholar Awards 2:00 p.m. - 3:30 p.m. OR59: Generation of 252 HLA Class I Genomic Sequences in a Single Sequencing Reaction Using DNA Barcodes and Single Molecule Real-Time (SMRT) DNA Sequencing Technology Dr. Neema P. Mayor, Anthony Nolan, London, United Kingdom; UCL Cancer Institute, London, United Kingdom Workshop: Wednesday, October 22 12:00 p.m. - 2:00 p.m. "Advances in Fully Phased HLA & KIR Typing Using SMRT® Sequencing" The Challenge of HLA Diversity in 2014 Prof. Steve Marsh, Anthony Nolan Research Institute & University College London Clinical HLA Typing on PacBio Platform Nezih Cereb, M.D., President & CEO, Histogenetics KIR Haplotypes: The Long and Short of It Martin Maiers, Ph.D., Director, Bioinformatics Research, National Bone Marrow Donor Program Posters: LBP04: Application of Single Molecule Real-Time (SMRT) Sequencing Technology for the Field 4 Level Genotyping of Classical HLA Loci LBP07: Evaluation of Multiplexing Strategies for HLA Genotyping Using PacBio Sequencing Technologies Attendees can also visit members of the PacBio staff at booth #307. For more information or to register for the PacBio workshop visit: http://programs.pacificbiosciences.com/l/1652/2014-08-22/2wst89.