From Earlier: ImmunoGen Announces Presentation of New Clinical Data for SAR3419

ImmunoGen, Inc. IMGN, a biotechnology company, today announced the presentation of new clinical data for the investigational compound, SAR3419, at the American Society of Clinical Oncology (ASCO) annual meeting taking place in Chicago, IL. SAR3419 uses ImmunoGen's Targeted Antibody Payload (TAP) technology and is a potential treatment for CD19+ non-Hodgkin's lymphoma (NHL) and other B-cell malignancies. The compound was created by ImmunoGen and licensed to Sanofi as part of a broader collaboration. The data reported today are from the Phase I evaluation that established the dosing schedule being used with SAR3419 in its Phase II evaluation. “We believe the findings reported today support that SAR3419 has the potential to become an important new therapy for key B-cell malignancies,” commented Daniel Junius, President and CEO. “These findings also add to the growing body of clinical data supporting that the utility of our TAP technology – and the depth of our product opportunities – extend well beyond any one compound to multiple types of cancers, antibodies, and product designs.” In its Phase I assessment, SAR3419 has been found to demonstrate activity across an array of NHL histological subtypes and in patients with rituximab (Rituxan®)-refractory and -responsive disease.1,2 Alternative dosing schedules were evaluated to establish the recommended Phase II schedule.