
Spruce Biosciences fell 57.3% from $115.61 to $49.34, behind the S&P 500's +10.5%. Its worst day was Apr 21 (−26.0%), and its low came Oct 14 at $38.98.
Nov 10, 2025 – Nov 9, 2026 · picked from earnings, analyst actions, headlines and the biggest daily moves
EPS of $-14.58 beat the $-15.56 estimate on $0.00 revenue (est. $200,000.00).
−2.6% · S&P 500 +0.2%
Spruce Biosciences shares rose 16.5%, while the S&P 500 fell 0.1%.
Story events cover the past 12 months · Times ET
+16.5%, the year's best day · S&P 500 −0.1%
Spruce Biosciences shares fell 20.1%, while the S&P 500 rose 0.1%.
−20.1% · S&P 500 +0.1%
EPS of $-36.25 missed the $-12.86 estimate on $0.00 revenue.
+11.2% · S&P 500 +0.9%
Spruce Biosciences shares fell 26.0%, while the S&P 500 fell 0.7%.
−26.0%, the year's worst day, on 649K shares, the year's heaviest volume · S&P 500 −0.7%
EPS of $-8.94 missed the $-7.32 estimate on $0.00 revenue.
+1.6% · S&P 500 +0.6%
EPS of $-6.68 missed the $-4.79 estimate on $0.00 revenue.
+1.4% · S&P 500 +0.3%
Spruce Biosciences shares rose 13.7%, while the S&P 500 fell 0.3%.
+13.7% · S&P 500 −0.3%
Spruce Biosciences closed at its lowest level of the year, 66.3% below where the year started.
−3.4% · S&P 500 −1.1%
EPS of $-8.51 was reported on $0.00 revenue.
+6.0% · S&P 500 +2.4%
Where it ended: a close of $49.34 on Nov 9, 2026.
Nothing in the past 12 months.
All SPRB dividend historyChart by ChartIQ. Events, ratings, quote and fundamentals from Benzinga APIs. Daily bars for SPRB and SPY from Benzinga historical bars. Not investment advice.