Spark Therapeutics Lacks Catalysts, Says Goldman Sachs


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Goldman Sachs is downgrading Spark Therapeutics Inc (NASDAQ:ONCE) after the pharma startup presented disappointing data on its hemophilia A gene therapy at the annual meeting of the American Society of Hematology on Monday.

The Analyst

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Goldman Sachs' Salveen Richter downgraded Spark Therapeutics from Buy to Neutral and lowered the price target to $58 from $106.

The Thesis

Sparks remains a leading gene therapy company, but it has limited value-driving catalysts in 2018, Richter said. (See Richter's track record here.) 

Goldman is projecting U.S. approval for Luxturna approval by Jan. 12, with a decent likelihood of a successful launch. There are also some preclinical assets that could enter clinic, like a liver disease-focused asset in-licensed from Genethon and drugs for Batten disease, Huntington's disease and the opthalmological disease Leber hereditary optic neuropathy, Richter said. 


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The price target of Spark Therapeutics was calculated by averaging the sum-of-parts valuation of $70 and the discounted cash flow valuation of $45, Richter said. Goldman projects the takeover probability for Spark at zero to 15 percent. 

The Price Action

Spark's stock dropped around 35 percent Monday after the company presented weak hemophilia A gene therapy data. The stock was trading 1.68 percent lower at $45.14 at the time of publication. 

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27% profit every 20 days?

This is what Nic Chahine averages with his option buys. Not selling covered calls or spreads… BUYING options. Most traders don’t even have a winning percentage of 27% buying options. He has an 83% win rate. Here’s how he does it.


Posted In: Analyst ColorDowngradesPrice TargetAnalyst RatingsGoldman SachsSalveen Richter