Synta Pharmaceuticals Inc was incorporated in Delware in March 2000 and commenced operations in July 2001. It is a biopharmaceutical company engaged in research, development and commercialization of novel oncology medicines that have the potential to change the lives of cancer patients. Its drug candidate, ganetespib, is a next generation Hsp90 inhibitor in Phase 3 development for non-small cell lung cancer (NSCLC) and in development program, including clinical trials for breast cancer, ovarian cancer and acute myeloid leukemia. In addition, it is developing several candidates from its proprietary Hsp90 inhibitor Drug Conjugate program (HDC Program), which leverages the preferential accumulation of Hsp90 inhibitors in tumors to selectively deliver an array of anti-cancer payloads. It also has an additional clinical-stage oncology candidate: elesclomol, a mitochondrial metabolism inhibitor. Its drug candidates and preclinical compounds are small molecules that can be readily synthesized by processes that it has developed. Its patent portfolio has a total of 867 patents and patent applications.