Bacterin Awarded Patent for Method to Produce Demineralized Bone Matrix

BELGRADE, Mont.--(BUSINESS WIRE)--

Bacterin International Holdings, Inc. (NYSE MKT: BONE), a leader in the development of revolutionary bone graft materials and coatings for medical applications, today announced that the United States Patent and Trademark Office has issued US Patent No. 8,574,825 entitled “Process for Demineralization of Bone Matrix with Preservation of Natural Growth Factors.” The issued claims in the patent are for a method to produce a demineralized cancellous bone matrix, such as Bacterin's OsteoSponge® product line. Bacterin has a pending divisional application in the United States to pursue protection on other aspects of its bone demineralization technology and is pursuing protection on related applications in Canada, Europe, and Korea.

Gregory Juda, Bacterin's CSO, commented “We are pleased to receive this patent that protects our proprietary Demineralized Bone products and recognizes the long term innovation of our Company. This patent further substantiates our core competency in demineralized bone matrix technology and we are committed to maintaining our role as a leader in advancing orthobiologic technology.”

The OsteoSponge®technology is two-fold; it allows for the allograft comprised of human bone to become compressible, while maintaining the spectrum of native growth factors inherent to bone. These growth factors are essential for the tissue regeneration process in the patients' body. Because of the compressible handling of the scaffold, and the presence of growth factors, Bacterin has been able to show fusion rates greater than 97 percent in peer reviewed, published studies. Bacterin was the first company to commercialize a compressible DBM sponge, marketed specifically for its handling characteristics, osteoconductive architecture, and osteoinductive properties for orthopedic bone grafting applications.

About Bacterin International Holdings

Bacterin International Holdings, Inc. (NYSE MKT: BONE) develops, manufactures and markets biologics products to domestic and international markets. These products are used in a variety of applications including enhancing fusion in spine surgery, relief of back pain, promotion of bone growth in foot and ankle surgery, promotion of cranial healing following neurosurgery and subchondral repair in knee and other joint surgeries.

Bacterin's Medical Device division develops, employs, and licenses coatings for various medical device applications. For further information, please visit www.bacterin.com.

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