Pfizer Receives EC Approval to Expand Use of XALKORI to First-Line Treatment of Adults with ALK-Positive Advanced NSCLC

Pfizer Inc. PFE today announced that the European Commission has approved a label update to expand use of XALKORI® (crizotinib) to first-line treatment of adults with anaplastic lymphoma kinase (ALK)-positive advanced non-small cell lung cancer (NSCLC). The Summary of Product Characteristics also has been updated to include efficacy data from PROFILE 1014, which demonstrated that XALKORI significantly prolonged progression-free survival (PFS) in previously untreated patients with ALK-positive advanced nonsquamous NSCLC when compared to standard platinum-based chemotherapy regimens.1 "The European Commission's decision to approve XALKORI in the first-line setting reinforces XALKORI's role as a standard of care for patients with ALK-positive advanced NSCLC," said Andreas Penk, MD, regional president See full press release