Concert Pharmaceuticals Initiates Phase 1 Multiple Ascending Dose Trial with CTP-656 for Cystic Fibrosis

Concert Pharmaceuticals, Inc. CNCE today announced that it has initiated a Phase 1 multiple ascending dose clinical trial with CTP-656. CTP-656 (deuterium-modified ivacaftor) is a novel, potentially disease-modifying treatment for cystic fibrosis for use as monotherapy as well as in combination with other CFTR modulators. Ivacaftor is commercially available under the name Kalydeco®. "CTP-656 has the potential to be an important new treatment, expanding therapeutic options for the cystic fibrosis community," said James Cassella, Ph.D., Chief Development Officer of Concert Pharmaceuticals. "We believe the development of CTP-656 as a once-daily dose could help address adherence issues documented with the current standard of care by offering a simplified treatment See full press release
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