Alexion Announces Study Presented at ASN 2015 Supports Effectiveness of Soliris in Preventing TMA Events in Patients with aHUS

Alexion Pharmaceuticals, Inc. ALXN today announced that researchers presented new data from a long-term follow-up study evaluating the effectiveness and safety of Soliris® (eculizumab) in preventing thrombotic microangiopathy (TMA)—the formation of blood clots in small blood vessels throughout the body—in patients with atypical hemolytic uremic syndrome (aHUS), a genetic, chronic, ultra-rare disease associated with vital organ failure and premature death.1,2,3 In this observational study, researchers reported a 74 percent lower TMA event rate with ongoing Soliris treatment with labeled dosing compared with discontinuation of Soliris therapy.4 These data were presented at the 2015 American Society of Nephrology (ASN) Annual Meeting in San Diego. "Patients with aHUS face a See full press release