TESARO Announces Inclusion of VARUBI in NCCN Antiemesis Guidelines

TESARO, Inc. TSRO today announced the decision of the National Comprehensive Cancer Network (NCCN) to include VARUBI™ (rolapitant) in the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Antiemesis Version 2.2015, as a recommended option in combination with other antiemetic agents for patients receiving both high emetic risk intravenous chemotherapy (HEC) and moderate emetic risk intravenous chemotherapy (MEC). Category 1, the highest level category of evidence and consensus, was granted to rolapitant for both HEC and MEC chemotherapy. VARUBI is a selective and competitive antagonist of human substance P/neurokinin 1 (NK-1) receptors, with a plasma half-life of approximately seven days. Results from three Phase 3 trials of VARUBI demonstrated a significant reduction in episodes of vomiting or use of rescue medication during the 25 to 120 hour period following administration of highly emetogenic and moderately emetogenic chemotherapy regimens. "Patients are at the center of all that we do, and are the reason we act with a sense of urgency and passion. We are grateful that NCCN has included VARUBI in their Antiemesis Guidelines so soon after our FDA approval, and we look forward to making VARUBI available to the See full press release