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Achillion Pharmaceuticals (NASDAQ: ACHN) climbed 44.71% to $6.15 after jumping 47.57% on Monday. The company reported the initiation of ACH-3422 dosing in HCV-infected patients.

Astea International (NASDAQ: ATEA) climbed 39.45% to $2.34. Astea Partner, Six-Axe Consultants, has been awarded a contract to implement Astea Alliance for Global IT services company in France.

Endeavour International (NYSE: END) shares jumped 35.58% to $1.41 after the company raised its Q2 production forecast from 9,000-10,000 boepd to 10.5-11.5 10,500-11,500 barrels of oil equivalent per day.

Receptos (NASDAQ: RCPT) shares surged 35.48% to $39.56 following Monday's announcement that RPC1063 has met primary efficacy endpoint.

Cherokee (NASDAQ: CHKE) gained 16.65% to $16.18 after the company reported Q1 earnings of $0.43 per share on revenue of $10.0 million.

MEI Pharma (NASDAQ: MEIP) shares rose 11.73% to $6.86 after the company announced high response rates for Phase II pracinostat study.

Christopher & Banks (NYSE: CBK) jumped 10.98% to $7.38 after the company reported better-than-expected quarterly earnings.

Scientific Games (NASDAQ: SGMS) shares surged 7.22% to $9.80 after the company named Gavin Isaacs as new CEO.

Isis Pharmaceuticals (NASDAQ: ISIS) rose 6.33% to $33.08. Isis Pharma earned a $15 million milestone payment from AstraZeneca (NYSE: AZN) for initiation of Phase 1 study of ISIS-AR Rx.

Avanir Pharmaceuticals (NASDAQ: AVNR) shares gained 3.93% to $5.55 after the company reported positive outcome of Phase IIIb COMPASS Trial.

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