Isis Pharmaceuticals to Present ISIS-SMN Rx Data at 2014 AAN Annual Meeting

Isis Pharmaceuticals, Inc.

announced today that it will host an investor event and a live webcast on Tuesday, April 29, 2014 at 6:00 p.m. Eastern Time to discuss the ISIS-SMNRx data presented at the 2014 American Academy of Neurology Annual Meeting. Isis Pharmaceuticals, Inc. Interested parties may register to attend the event in Philadelphia, PA, or access the webcast on the "Investors & Media" page at www.isispharm.com. The webcast will remain posted on Isis' Web site for a limited time.