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Weibo (NASDAQ: WB) shares moved up 15.61% to $23.40. The volume of Weibo shares traded was 5469% higher than normal. Weibo closed its first day of trading at $20.17, an 18 percent gain for IPO investors.

Sarepta Therapeutics (NASDAQ: SRPT) shares rose 42.49% to $34.77. The volume of Sarepta Therapeutics shares traded was 1704% higher than normal. Sarepta will file NDA for Eteplirsen for the treatment of Duchenne Muscular Dystrophy by the year-end.

AstraZeneca PLC (NYSE: AZN) shares climbed 5.54% to $67.01. The volume of AstraZeneca shares traded was 400% higher than normal. AstraZeneca jumped on a report of potential acquisition by Pfizer (NYSE: PFE).

Hub Group (NASDAQ: HUBG) surged 3.13% to $44.20. The volume of Hub Group shares traded was 388% higher than normal. Hub Group reported its Q1 earnings of $0.33 per share on revenue of $848.40 million. Longbow Research upgraded Hub Group from Neutral to Buy.

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