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GameStop (NYSE: GME) dropped 18.51% to $36.93 after the company cut its profit outlook for the holiday quarter.

Rexahn Pharmaceuticals (NYSE: RNN) plummeted 16.06% to $1.34 after the company initiated Phase IIa clinical trial of Archexin® in patients with metastatic renal cell carcinoma.

Silicon Graphics International (NASDAQ: SGI) dropped 14.18% to $11.92 after the company issued a weak forecast.

The Descartes Systems Group (NASDAQ: DSGX) dropped 14.07% to $13.50. Descartes' PEG ratio is 5.66.

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