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GSE Holdings (NYSE: GSE) dropped 43.89% to $0.78. GSE's PEG ratio is -0.21.

SodaStream International (NASDAQ: SODA) plummeted 21.48% to $39.17 after the company lowered its FY13 forecast.

Prosensa Holding NV (NASDAQ: RNA) dropped 19.79% to $4.50 after the company reported that it has regained all rights from GlaxoSmithKline (NYSE: GSK) to drisapersen. The company will also retain rights to all other programs for the treatment of Duchenne Muscular Dystrop.

Intercept Pharmaceuticals (NASDAQ: ICPT) dropped 19.37% to $359.48 after the company announced an additional detail about FLINT Trial provided by NIDDIK.

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