Benzinga's Top #PreMarket Gainers

NuPathe

surged 50.43% to $3.46 in the pre-market session after the company agreed to be acquired by Endo Health Solutions

for $2.85 per share in cash. Solta Medical

soared 21.05% to $2.53 in the pre-market trading after Valeant Pharmaceuticals

agreed to acquire Solta Medical for $2.92 per share in cash. AcelRx Pharmaceuticals

shares jumped 9.15% to $8.95 in pre-market trading after the company announced the collaboration for EU commercialization of ZALVISO. YRC Worldwide

shares gained 3.28% to $12.90 in the pre-market. YRC Worldwide shares have jumped 81.28% over the past 52 weeks, while the S&P 500 index has gained 24.12% in the same period.