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Vanda Pharmaceuticals (NASDAQ: VNDA) shares gained 17.48% to $15.32 in the pre-market after the FDA Advisory Committee recommended the approval of HETLIOZ.

Agilent Technologies (NYSE: A) surged 6.25% to $53.70 in the pre-market session after the company reported an upbeat Q4 profit.

Tile Shop Holdings (NASDAQ: TTS) shares jumped 4.71% to $13.56 in pre-market trading. Citigroup downgraded Tile Shop from Buy to Neutral.

Arena Pharmaceuticals (NASDAQ: ARNA) soared 3.70% to $5.30 in the pre-market trading after WallachBeth initiated coverage on the stock with a Buy rating.

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