ACADIA Pharmaceuticals ACAD today
announced that it has initiated a Phase II feasibility trial designed to
examine the efficacy and safety of pimavanserin as a treatment for
patients with Alzheimer's disease psychosis (ADP). No drug is approved
in the United States to treat ADP and the off-label use of current
antipsychotics is linked to increased mortality, serious adverse events,
and cognitive decline in elderly patients with dementia-related
psychosis.
“The development of psychosis and related behavioral disturbances in
patients with Alzheimer's disease carries a poor prognosis and often has
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