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Novo Nordisk A/S (NYSE: NVO) shares dropped 13.43% to $166.36 in pre-market trading. Novo Nordisk shares have surged 40.27% over the past 52 weeks, while the S&P 500 index has gained 12.29% in the same period.

Caesars Entertainment (NASDAQ: CZR) dipped 7.12% to $12.92 in the pre-market session. Caesars Entertainment's trailing-twelve-month ROE is -179.12%.

BlackBerry (NASDAQ: BBRY) shares fell 4.06% to $15.82 in the pre-market trading. Bed BlackBerry's trailing-twelve-month profit margin is -6.90%.

Sarepta Therapeutics (NASDAQ: SRPT) dipped 3.15% to $28 in the pre-market session. Sarepta's PEG ratio is -0.51.

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