Response Genetics Launches ROS1 Testing for Lung Cancer

Response Genetics RGDXannounced today the launch of testing for ROS1 gene rearrangements.  Recently, the Massachusetts General Hospital Cancer Center ("MGH") published studies showing that ROS1 driven tumors are sensitive to the FDA approved drug XALKORI®1 (crizotinib)2 to treat non-small-cell lung cancer ("NSCLC") patients with ALK gene rearrangements.  Tumors driven by rearrangements in the ROS1 gene represent an additional 1 to 2 percent of patients who may be candidates for crizotinib therapy.3 The company will offer both fluorescence in situ hybridization ("FISH") and polymerase chain reaction ("PCR") based ROS1 translocation testing.       "We are pleased to add ROS1 to our growing test menu," said Thomas Bologna, chairman and CEO of Response Genetics.  "We believe the dual option of FISH and PCR represent a unique offering and is consistent with our Leave No Stone Unturned program whereby we go to great lengths to help patients receive optimal therapy.  While FISH is the technology that has been used for ROS1 See full press release