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Bankrate (NYSE: RATE) shares dipped 26.28% to $10.69 at 10:05 am. Bankrate issued downbeat forecast for the third quarter.

Clearwire (NASDAQ: CLWR) shares lost 16.05% to $2.26. Clearwire's trailing-twelve-month operating margin is -93.80%.

Homeowners Choice (NASDAQ: HCIIW) fell 13.25% to $6.61. Homeowners Choice projects its shares to start trading on the NYSE on October 25, 2012, under the new ticker symbol "HCI."

Isis Pharmaceuticals (NASDAQ: ISIS) dropped 12.28% to $11.54. Isis Pharmaceuticals' trailing-twelve-month ROE is -39.35%.

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