Benzinga's Top Pre-Market Gainers

Orexigen Therapeutics OREX surged 4.11% to $7.35 in the pre-market session. Orexigen Therapeutics shares have surged 338.51% over the past 52 weeks, while the S&P 500 index has gained 3.93% in the same period. Visa V added 4.03% to $129.09 in the pre-market session. Visa, MasterCard MA and various banks have agreed to pay $7.3 billion to settle merchant lawsuits. Human Genome Sciences HGSI moved up 3.53% to $14.06 in the pre-market session. GlaxoSmithKline Plc GSK lifted its hostile takeover offer to buy Human Genome Sciences to around $14 a share, according to Reuters. Mastercard MA soared 3.35% to $444.01 in the pre-market trading. Mastercard's PEG ratio is 1.00.