Benzinga's Top Pre-Market Losers

Repligen

shares dropped 24.66% to $3.30 in pre-market trading. Repligen received a Complete Response Letter from the US Food & Drug Administration regarding the company's New Drug Application for RG1068. Ryder System

dipped 8.22% to $37.40 in the pre-market session. Ryder cut its fiscal second-quarter and full-year earnings estimates. Darden Restaurants

dipped 2.76% to $49.00 in the pre-market session. Darden reported a 10% rise in its fiscal fourth-quarter earnings. Electronic Arts

shares fell 2.08% to $11.75 in the pre-market trading. Analysts at Citigroup downgraded Electronic Arts from “buy” to “neutral.”