Midday Gainers

Ardelyx Inc. ARDX +32% - Wednesday morning the company reported positive results from its 371 patient Phase 2b clinical trial evaluating tenapanor.

Angie’s List Inc. ANGI +22% - On Wednesday, a report surfaced that the company is exploring strategic options including a possible sale.

Tekmira Pharmaceuticals Corp. TKMR +18% - Following the first reported case of Ebola in the U.S. Shares of Tekmira are up due to the company’s experimental drug used to treat Ebola.

Portola Pharmaceuticals Inc PTLA +15% - On Wednesday, the company announced its first Phase 3 study of andexanet alfa met its primary and secondary endpoints with statistical significance.

Acuity Brands Inc. AYI + 13% - Wednesday morning the company reported earnings that beat expectations of both revenues and earnings.

The New York Times Company NYT +8.5% - The company reported that is will cut 100 jobs or 7.5 percent of its news its newsroom staff.

The Babcock & Wilcox Company BWC +7% - On Wednesday, the company announced that is it exploring the separation of the company's Power Generation Business and Government & Nuclear Operations Business into two publicly traded companies.