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Updated: Sep 27, 2026
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Seaport Therapeutics

NASDAQ:SPTX·Stock Analysis Report
Day Range
$18.49 - $18.85
Market Cap
1.15B
P/E Ratio
0.0000
Avg Value
$21.62
Year Range
$14.85 - $28.38
$18.49-$0.20 (-1.07%)
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General Information
Seaport Therapeutics Inc is a clinical-stage therapeutics company. The company focuses on invention and development of new medicines for patients with depression, anxiety, and other debilitating neuropsychiatric disorders.

The company identified clinically validated mechanisms with established efficacy and safety profiles, historically limited by high first-pass metabolism, low bioavailability, and side effects. The company's pipeline products are based on Glyph, company's lymphatic-targeting prodrug technology is designed to bypass first-pass metabolism and thereby enhance a drug's oral bioavailability and reduce side effects.

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Seaport Therapeutics (SPTX) Stock Graph
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How We Grade Seaport Therapeutics (SPTX)

We grade stocks based on past performance, their future growth potential, intrinsic value, dividend history, and overall financial health.

The chart below shows how we grade Seaport Therapeutics (SPTX) across the board compared to its closest peers.

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Benzinga Edge Rankings

Benzinga Edge stock rankings give you four critical scores to help you identify the strongest and weakest stocks to buy and sell.

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Peer Ratings

See how Seaport Therapeutics compares to its peers in these key performance metrics from Benzinga Rankings.

Top Peers
Value
Quality
Growth
Momentum
Short
Medium
Long
LTGOLatigo Biotherapeutics
N/A
N/A
N/A
N/A
AMPHAmphastar Pharma
58.37
65.88
20.12
86.05
LBRXLB Pharmaceuticals
N/A
N/A
N/A
96.82
CRONCronos Group
N/A
N/A
47.48
87.92
Short: price trend over the last couple of months
Medium: price trend over the last couple of quarters
Long: price trend over the past year
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Benzinga Rankings give you vital metrics on any stock – anytime.
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Future Growth
Our estimate of future price growth is based on an aggregation of 3 analyst ratings over the past 3 months and their 12-month price targets.

Below, you can see that analysts are estimating a 12-month price target range of $32.00 - $50.00 with an average of $46.33

115.30%
Expected movement for Seaport Therapeutics (SPTX) over the next 12 months
Based on these rankings

Recent Ratings for Seaport Therapeutics (SPTX)

HC Wainwright & Co.
Date:
Sep 10, 2026
Action:
Reiterates
Prev. Target:
$50.00
New Target:
$50.00
HC Wainwright & Co.
Date:
Aug 20, 2026
Action:
Reiterates
Prev. Target:
$50.00
New Target:
$50.00
HC Wainwright & Co.
Date:
Aug 4, 2026
Action:
Reiterates
Prev. Target:
$50.00
New Target:
$50.00
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Past Performance
How has Seaport Therapeutics (SPTX) performed over the past 5 years?

The two main factors that we consider when analyzing past performance is overall return and volatility

Using these two metrics, we can determine if this stock gave its investors enough return for the risk that they took on by owning it. This is measured by the sharpe ratio, which has been used as a primary measure of risk/reward trade-off for almost 60 years.

This ratio can be interpreted as the amount of return an investor has received for the amount of risk that they took on by owning the stock over that timeframe.

Seaport Therapeutics (SPTX) sharpe ratio over the past 5 years is -0.0176 which is considered to be below average compared to the peer average of 0.1159