The SPDR S&P 500 ETF Trust (NYSE:SPY) declined by 9.62% in September – its largest decline in 2022. The Fidelity NASDAQ Composite Index ETF (NASDAQ:ONEQ) and the SPDR Dow Jones Industrial Average ETF (NYSE:DIA) mimicked this downward trend, showing monthly decreases in September of 10.54% and 8.98%, respectively.

OTC Markets Group Inc.’s (OTCQX:OTCM) regulated markets experienced a slight increase in total monthly volume, recording $39.5 billion in September compared to $39.3 billion in August.

A Dive Into The OTCQX Best Market’s Most-Active List

The OTCQX Best Market recorded $7.3 billion in trading volume in September, a slight increase over the $6.9 billion traded in August.

Despite Ethereum’s successful completion of the Merge, trading volume in Grayscale Ethereum Trust (OTCQX:ETHE) waned in September, dropping the security to third on the OTCQX Best Market’s Most Active list. Steadfast performers Roche Holding AG (OTCQX:RHHBY) and Grayscale Bitcoin Trust (OTCQX:GBTC) slotted into first and second place, respectively.

Additionally, OTCQX’s top 10 most-active securities experienced a slight reshuffle in September, welcoming previously familiar faces in Danone (OTCQX:DANOY) and in Deutsche Telekom AG (OTCQX:DTEGY) and Akzo Nobel N.V. (OTCQX:AKZOY). The three newcomers displace BASF SE (OTCQX:BASFY), Anglo American PLC (OTCQX:NGLOY) and Imperial Brands PLC (OTCQX:IMBBY) in the top 10 most-active securities list.

Other notable movers:

J Sainsbury PLC (OTCQX:JSAIY) claimed the 28th spot on the OTCQX’s Most Active list, experiencing a 203% increase in trading volume.

Koninklijke Ahold Delhaize N.V. (OTCQX:ADRNY) claimed the 15th spot on the OTCQX’s Most Active list, experiencing a 127% increase in trading volume.

The OTCQB Venture Market Experiences A Reshuffle

The OTCQB Venture Market recorded $642.6 million in trading volume in September, an increase from both July’s $463 million and August’s $601 million trading volume figures.

Like the OTCQX Best Market, the OTCQB Venture Market’s top 10 Most Active list for the month saw new entries. Specifically, Todos Medical Ltd. (OTCQB:TOMDF) and American Lithium Corp. (OTCQB:LIACF) made way for Global Tech Industries Group Inc. (OTCQB:GTII) and Know Labs Inc. (OTCQB:KNWN).

Similar to August, the OTCQB Venture Market witnessed a number of novelties in September. In addition to two new companies on the top 10 Most Active List, the constituents of the list experienced a shakeup. Biotechnology company CytoDyn Inc. (OTCQB:CYDY), for example, dropped from most traded to seventh-most traded security, while newcomer Global Tech Industries took a giant leap all the way to first place. Lithium miner Lake Resources N.L. (OTCQB:LLKKF) experienced a similar jump, rising to second place from eighth place last month.

Other notable movers:

Silver Mountain Resources Inc. (OTCQB:AGMRF) climbed to 11th place on the Most Active list and recorded an $8.9 million rise in trading volume compared to last month.

Know Labs Inc. climbed to 10th place on the Most Active list for the OTCQB Venture Market and recorded a $7.7 million rise in trading volume compared to last month.

BioLargo Inc. (OTCQB:BLGO) climbed to 23rd place on the Most Active list and recorded a $2.3 million rise in trading volume compared to last month.

The OTCQX And OTCQB Top 10

Below are the top 10 most actively traded securities on the OTCQX Best Market and OTCQB Venture Market in September.

OTCQX Top 10:

Company Name	Symbol	September Dollar Volume
Roche Holding Ltd.	RHHBY	$1,707,901,205
Grayscale Bitcoin Trust (BTC)	GBTC	$785,442,416
Grayscale Ethereum Trust (ETH)	ETHE	$685,952,488
adidas AG	ADDYY	$317,175,529
BNP Paribas	BNPQY	$295,090,950
Deutsche Telekom AG	DTEGY	$268,213,144
Computer Services Inc.	CSVI	$216,708,362
Akzo Nobel N.V.	AKZOY	$167,395,328
Danone	DANOY	$167,340,096
Infineon Technologies AG	IFNNY	$158,503,975

OTCQB Top 10:

Company Name	Symbol	September Dollar Volume
Global Tech Industries Group Inc.	GTII	$119,304,739
Lake Resources N.L.	LLKKF	$24,528,742
Stemtech Corp.	STEK	$22,459,406
Northwest Biotherapeutics Inc.	NWBO	$21,313,034
American Battery Technology Co.	ABML	$16,729,817
Fannie Mae	FNMA	$15,086,158
CytoDyn Inc.	CYDY	$14,135,987
Netlist Inc.	NLST	$13,413,921
Freddie Mac	FMCC	$12,995,635
Know Labs Inc.	KNWN	$10,652,167

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Featured photo by Kelly Sikkema on Unsplash

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