Bayer's Kidney Disease Drug Disappoints On Cutting Cardiovascular Death


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  • Bayer AG (OTC:BAYRYreported disappointing results from its approved med Kerendia (finerenone) didn’t reach significance on all-cause mortality in a pooled analysis of two Phase 3 trials of the drug.
  • Last July, the FDA approved the drug to slow chronic kidney disease progression in patients with CKD associated with type 2 diabetes. 
  • In a pooled analysis of the company’s Phase 3 FIDELIO-DKD and FIGARO-DKD studies, Kerendia did not reach statistical significance on all-cause or cardiovascular mortality. 
  • Bayer said the drug “narrowly missed” that mark and that an on-treatment analysis provided a more favorable picture.
  • Related: Bristol Myers-JNJ Partnered Secondary Stroke Drug Misses Endpoint, But Companies See Enough Potential For Phase 3 Trials.
  • Finerenone was found to reduce sudden cardiac death vs. placebo significantly.
  • All-cause mortality rates were 8.5% in the Kerendia-treated group and 9.4% in the placebo.
  • Bayer said CV mortality made up the most common cause of death in the trial, comprising 4.9% of the Kerendia group and 5.6% of the placebo group.
  • Price Action: BAYRY shares are down 3.82% at $12.83 on the last check Monday.

27% profit every 20 days?

This is what Nic Chahine averages with his option buys. Not selling covered calls or spreads… BUYING options. Most traders don’t even have a winning percentage of 27% buying options. He has an 83% win rate. Here’s how he does it.


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