Novocure Q4 Earnings Miss Street View, New Data Shows TTFields Initiates Downstream Anti-Tumor Response


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A new study published in the Journal of Clinical Investigation (JCI) finds treatment with Novocure Ltd's (NASDAQ:NVCR) Tumor Treating Fields (TTFields) mediated cell disruption activates the immune system and triggers an anti-tumor cell response.

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  • Preclinical research has shown that TTFields may induce a pro-inflammatory and broader immunological effect on tumor cells. 
  • Data demonstrated that treatment with TTFields directly disrupted the nuclear envelope of glioblastoma (GBM) tumor cells, leading to leakage of DNA that activates the cGAS/STING and AIM2 signaling pathways, driving early anti-tumor immune responses. 
  • Related: Novocure Posts Data For Tumor Treating Fields In Brain Tumor Trial.
  • Further, a genetic signature was identified in patients treated with TTFields therapy, indicating an acquired immune response. 
  • Earnings: Novocure posted Q4 sales of $133.2 million, down 7.5% Y/Y, missing the consensus of $135.42 million.
  • The gross margin for the quarter was 78%.
  • The Company posted an EPS loss of $(0.25), compared to the income of $0.05, missing the consensus of $(0.10).
  • There were 3,587 active patients on therapy, +5% Y/Y.
  • Guidance: The Company expects to achieve active patient growth between 2% to 5% in 2022, in-line with the growth rate experienced in Q4 FY21.
  • Price Action: NVCR shares are down 2.93% at $70.82 during the market session on the last check Thursday.

27% profit every 20 days?

This is what Nic Chahine averages with his option buys. Not selling covered calls or spreads… BUYING options. Most traders don’t even have a winning percentage of 27% buying options. He has an 83% win rate. Here’s how he does it.


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