Bristol Myers-2seventy Partnered Abecma Cuts Risk Of Disease Progression, Death By 51% In Pretreated Myeloma Patients


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  • Bristol-Myers Squibb & Co (NYSE:BMY) and 2seventy bio Inc (NASDAQ:TSVT) announced the first publication and presentation of results from the KarMMa-3 Phase 3 study evaluating Abecma (idecabtagene vicleucel) in The New England Journal of Medicine.
  • The study compared Abecma with standard combination regimens in adults with relapsed and refractory multiple myeloma after two to four prior lines of therapy.
  • At a median follow-up of 18.6 months, Abecma demonstrated a clinically meaningful and statistically significant improvement in progression-free survival compared with standard regimens, with a median PFS of 13.3 months vs. 4.4 months, representing a 51% reduction in risk of disease progression or death.
  • The overall response rate also met statistical significance, with 71% treated with Abecma achieving a response and 39% achieving a complete response or stringent complete response. 
  • Also Read2seventy Bio Shares Jump On Positive Data From Bristol Myers-Partnered Cancer Immunotherapy.
  • In comparison, 41% who received standard regimens achieved a response, with 5% experiencing a complete response or stringent complete response. 
  • Responses with Abecma were durable, with a median duration of 14.8 months compared with 9.7 months for standard regimens. 
  • Bristol-Myers Squibb and 2seventy bio intend to include these data in a planned supplemental Biologics License Application submission to the FDA in 2023. 
  • Price Action: TSVT shares are down 0.23% at $13.02 on the last check Friday.

27% profit every 20 days?

This is what Nic Chahine averages with his option buys. Not selling covered calls or spreads… BUYING options. Most traders don’t even have a winning percentage of 27% buying options. He has an 83% win rate. Here’s how he does it.


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